GO term number of genes involved median of Ka/Ks ATP biosynthesis 1 0.452513966 ATP catabolism 2 0.160173338 ATP metabolism 4 0.220904451 ATP synthesis coupled electron transport 6 0.225704144 ATP synthesis coupled electron transport (sensu Eukaryota) 6 0.225704144 B cell activation 8 0.264143264 B cell differentiation 5 0.092664093 B cell mediated immunity 3 0.092664093 B cell proliferation 3 0.092664093 BMP signaling pathway 1 0.098305085 CMP-sialic acid transport 1 0.356687898 D-amino acid catabolism 1 0.390361446 D-amino acid metabolism 1 0.390361446 D-ribose metabolism 1 0.854166667 DNA alkylation 13 0.317708333 DNA damage checkpoint 3 0.675496689 "DNA damage response\, signal transduction " 7 0.230769231 "DNA damage response\, signal transduction resulting in induction of apoptosis " 4 0.157827679 DNA dealkylation 1 0.332574032 DNA metabolism 242 0.283177438 DNA methylation 13 0.317708333 DNA modification 19 0.284722222 DNA packaging 75 0.262987013 DNA recombination 34 0.280469083 DNA repair 93 0.297491039 DNA replication 73 0.252380952 DNA replication checkpoint 3 0.424892704 DNA replication initiation 11 0.14416476 DNA restriction-modification system 2 0.234253003 DNA strand elongation 2 0.36765873 DNA synthesis during DNA repair 1 0.924855491 DNA topological change 7 0.156 DNA transposition 2 0.414771654 DNA unwinding 3 0.575630252 DNA-dependent DNA replication 33 0.287066246 ER to Golgi transport 19 0.322580645 ER-nuclear signaling pathway 3 0.513157895 ER-nuclear sterol response pathway 1 0.432098765 G-protein coupled receptor protein signaling pathway 220 0.336290072 "G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating) " 35 0.314285714 "G-protein signaling\, coupled to cAMP nucleotide second messenger " 24 0.305778878 "G-protein signaling\, coupled to cGMP nucleotide second messenger " 1 0.314606742 "G-protein signaling\, coupled to cyclic nucleotide second messenger " 33 0.314606742 G0 to G1 transition 1 0.1015625 G1 phase 7 0.326086957 G1 phase of mitotic cell cycle 7 0.326086957 G1/S transition of mitotic cell cycle 15 0.25 G2/M transition of mitotic cell cycle 15 0.25 GDP-mannose biosynthesis 1 0.071340713 GDP-mannose metabolism 1 0.071340713 Golgi to endosome transport 1 0.231527094 Golgi vesicle transport 40 0.310326087 I-kappaB kinase/NF-kappaB cascade 46 0.313306569 JAK-STAT cascade 18 0.219601156 JNK cascade 20 0.348288924 L-alanine transport 2 0.319622052 L-amino acid transport 11 0.162601626 L-asparagine transport 2 0.319622052 L-cystine transport 2 0.196527151 L-glutamate transport 7 0.123966942 L-glutamine transport 2 0.319622052 L-histidine transport 2 0.319622052 L-phenylalanine biosynthesis 1 0.364383562 L-phenylalanine catabolism 6 0.188752251 L-phenylalanine metabolism 7 0.203463203 L-serine metabolism 6 0.263114429 M phase 105 0.252380952 M phase of meiotic cell cycle 23 0.253424658 M phase of mitotic cell cycle 84 0.260289171 MAPKKK cascade 48 0.303534877 N-acetylglucosamine metabolism 3 0.355102041 N-terminal protein amino acid modification 1 0.092 NAD biosynthesis 1 0.285077951 Notch receptor processing 4 0.302623656 Notch signaling pathway 11 0.282666667 O-glycoside metabolism 1 0.421800948 RNA 3'-end processing 5 0.065060241 RNA catabolism 4 0.350839887 RNA editing 1 0.103030303 RNA elongation 3 0.435483871 RNA interference 1 0.251101322 "RNA interference\, targeting of mRNA for destruction " 1 0.251101322 RNA localization 12 0.223593952 RNA metabolism 156 0.292900056 RNA methylation 1 0.103982301 RNA modification 29 0.290322581 RNA processing 121 0.290322581 RNA splicing 33 0.306666667 "RNA splicing\, via transesterification reactions " 5 0.264631043 RNA transport 12 0.223593952 RNA-dependent DNA replication 2 0.808571429 RNA-mediated gene silencing 1 0.251101322 RNA-mediated posttranscriptional gene silencing 1 0.251101322 RNA-nucleus export 12 0.223593952 Rac protein signal transduction 1 1.077235772 Ras protein signal transduction 12 0.304403131 Rho protein signal transduction 9 0.420168067 S phase 1 0.114613181 S phase of mitotic cell cycle 1 0.114613181 SRP-dependent cotranslational protein-membrane targeting 1 0.274647887 T cell activation 8 0.258534715 T cell differentiation 5 0.259493671 T cell proliferation 1 0.360313316 T cell selection 1 0.36682243 T-helper 1 cell differentiation 2 0.165967068 T-helper 1 type immune response 4 0.343793022 T-helper 2 cell differentiation 2 0.165967068 T-helper 2 type immune response 1 0.25462963 T-helper cell differentiation 3 0.167682927 UV protection 3 0.181459566 Wnt receptor signaling pathway 39 0.263736264 acetyl-CoA biosynthesis 1 0.473404255 acetyl-CoA catabolism 14 0.144544582 acetyl-CoA metabolism 16 0.144544582 acetylcholine transport 1 0.042654028 acid secretion 1 0.35046729 acidic amino acid transport 7 0.123966942 actin cytoskeleton organization and biogenesis 18 0.451755882 actin filament polymerization 6 0.402236994 actin filament severing 3 0.30044843 actin filament-based movement 10 0.14405783 actin filament-based process 28 0.295438736 actin polymerization and/or depolymerization 6 0.402236994 activated T cell proliferation 1 0.360313316 activation of JNK 8 0.163325048 activation of MAPK 20 0.163325048 activation of MAPKK 4 0.209713622 activation of MAPKKK 4 0.371569124 acute-phase response 9 0.23655914 acyl-CoA metabolism 4 0.344740066 acylglycerol biosynthesis 3 0.314285714 acylglycerol catabolism 1 1.243055556 acylglycerol metabolism 10 0.356916506 adenine metabolism 1 0.512027491 adenine salvage 1 0.512027491 adenylate cyclase activation 5 0.244939271 adult heart development 2 0.343537415 aerobic respiration 17 0.14861461 age-dependent response to reactive oxygen species 1 1.300884956 aging 4 0.23754688 alcohol biosynthesis 15 0.263929619 alcohol catabolism 30 0.298584461 alcohol metabolism 124 0.295707344 aldehyde metabolism 12 0.302531511 alpha-ketoglutarate transport 3 0.127147766 amine biosynthesis 38 0.311805872 amine catabolism 27 0.225519288 amine metabolism 157 0.287671233 amine transport 44 0.253126166 amino acid activation 24 0.35123882 amino acid and derivative metabolism 131 0.273469388 amino acid biosynthesis 27 0.247159091 amino acid catabolism 27 0.225519288 amino acid derivative biosynthesis 12 0.511033734 amino acid derivative catabolism 2 0.664761198 amino acid derivative metabolism 20 0.366909091 amino acid metabolism 115 0.260869565 amino acid transport 38 0.237675317 amino sugar catabolism 1 0.657894737 amino sugar metabolism 4 0.341064534 aminoglycan biosynthesis 9 0.382978723 aminoglycan catabolism 6 0.143691939 aminoglycan metabolism 23 0.3514377 aminophospholipid transport 1 0.20718232 ammonium transport 3 0.215158924 anaphase 4 0.291457475 androgen biosynthesis 1 0.204359673 androgen catabolism 1 0.204359673 androgen metabolism 2 0.188646002 angiogenesis 23 0.312977099 anion transport 97 0.363636364 anterior/posterior axis specification 2 0.125946137 anterior/posterior pattern formation 2 0.125946137 anti-apoptosis 31 0.301886792 anti-inflammatory response 4 1.786281478 antibacterial humoral response 1 0.123529412 antibacterial humoral response (sensu Vertebrata) 1 0.123529412 antibiotic biosynthesis 2 0.780001016 antibiotic metabolism 2 0.780001016 antigen presentation 3 0.371794872 "antigen presentation\, endogenous antigen " 1 0.037453184 "antigen presentation\, endogenous peptide antigen " 1 0.037453184 "antigen presentation\, peptide antigen " 1 0.037453184 antigen processing 9 0.690410959 "antigen processing\, endogenous antigen via MHC class I " 4 0.280230187 "antigen processing\, exogenous antigen via MHC class II " 3 0.767148014 antimicrobial humoral response 15 0.28440367 antimicrobial humoral response (sensu Vertebrata) 15 0.28440367 apical protein localization 1 1.212328767 apocarotenoid metabolism 1 0.331707317 apoptosis 198 0.311886305 apoptotic mitochondrial changes 1 0.577922078 apoptotic program 12 0.537236901 appendage morphogenesis 3 0.36682243 arachidonic acid metabolism 3 0.18707483 arginine biosynthesis 2 0.123770253 arginine catabolism 3 0.159468439 arginine metabolism 5 0.159468439 aromatic amino acid family biosynthesis 1 0.364383562 aromatic amino acid family catabolism 8 0.244270577 aromatic amino acid family metabolism 9 0.285077951 aromatic compound biosynthesis 1 0.364383562 aromatic compound catabolism 9 0.203463203 aromatic compound metabolism 32 0.294124634 arsonoacetate metabolism 1 1.977272727 asparagine metabolism 1 0.474164134 aspartate family amino acid biosynthesis 6 0.369129545 aspartate family amino acid catabolism 5 0.441416894 aspartate family amino acid metabolism 13 0.441416894 aspartate metabolism 4 0.440169114 astrocyte activation 1 0.452054795 asymmetric cell division 2 0.186192853 asymmetric protein localization 1 1.212328767 autophagic vacuole formation 1 0.394117647 autophagy 6 0.387780473 autophosphorylation 8 0.218685031 axis specification 4 0.125946137 axon cargo transport 2 0.244482972 axon guidance 22 0.311184682 axonal fasciculation 1 0.219839142 axonogenesis 30 0.319109909 base-excision repair 5 0.468581688 basic amino acid transport 3 0.230452675 beta-amyloid metabolism 1 0.098159509 bicarbonate transport 1 0.220512821 bile acid biosynthesis 1 0.395604396 bile acid metabolism 4 0.453574467 bilirubin conjugation 2 0.170870667 biogenic amine biosynthesis 11 0.53699284 biogenic amine catabolism 2 0.664761198 biogenic amine metabolism 18 0.399732621 biomineral formation 11 0.201954397 biopolymer biosynthesis 8 0.399909593 biopolymer catabolism 245 0.314984709 biopolymer metabolism 658 0.294262532 biosynthesis 419 0.290836653 biotin metabolism 1 0.086378738 blastoderm segmentation 2 0.125946137 blood coagulation 51 0.307692308 blood vessel development 25 0.327272727 blood vessel morphogenesis 25 0.327272727 body growth 1 0.155172414 bone mineralization 2 0.200172909 bone remodeling 11 0.201954397 brain development 20 0.38120861 branched chain family amino acid catabolism 2 0.118189369 branched chain family amino acid metabolism 5 0.15 brown fat cell differentiation 1 0.569230769 cAMP biosynthesis 14 0.23690441 cAMP metabolism 14 0.23690441 cAMP-mediated signaling 24 0.305778878 cGMP biosynthesis 6 0.429520344 cGMP metabolism 6 0.429520344 cGMP-mediated signaling 2 0.557303371 calcium ion homeostasis 16 0.19914399 calcium ion sensing 4 0.194834574 calcium ion transport 38 0.223521764 calcium-mediated signaling 10 0.265020892 carbohydrate biosynthesis 38 0.370875223 carbohydrate catabolism 43 0.255591054 carbohydrate mediated signaling 1 0.123529412 carbohydrate metabolism 209 0.26744186 carbohydrate transport 13 0.355263158 carboxylic acid biosynthesis 27 0.18707483 carboxylic acid catabolism 1 0.047619048 carboxylic acid metabolism 209 0.264094955 carboxylic acid transport 56 0.249974648 cardiac cell differentiation 1 0.612244898 cardioblast differentiation 1 0.612244898 carnitine biosynthesis 2 0.888871955 carnitine metabolism 2 0.888871955 carnitine transport 3 0.121621622 carotenoid biosynthesis 1 0.188908146 carotenoid metabolism 1 0.188908146 cartilage condensation 10 0.217174525 cartilage development 10 0.217174525 caspase activation 6 0.389180402 catabolism 393 0.302788845 catecholamine biosynthesis 3 0.685185185 catecholamine metabolism 7 0.352 cation homeostasis 41 0.237623762 cation transport 212 0.263419743 cell activation 21 0.257575758 cell adhesion 331 0.316708229 cell aging 1 0.139293139 cell communication 1375 0.309608541 cell cycle 319 0.257217848 cell cycle arrest 28 0.294783779 cell cycle checkpoint 15 0.403409091 cell death 214 0.306153187 cell development 7 0.321637427 cell differentiation 152 0.306585062 cell division 89 0.287179487 cell fate commitment 5 0.172413793 cell fate determination 5 0.172413793 cell glucose homeostasis 1 0.569230769 cell growth 56 0.292480862 cell homeostasis 48 0.272238204 cell ion homeostasis 45 0.248878924 cell killing 2 0.361850305 cell maturation 3 1.212328767 cell migration 48 0.311965582 cell motility 121 0.303921569 cell organization and biogenesis 324 0.260925478 cell projection biogenesis 5 0.208108108 cell projection organization and biogenesis 5 0.208108108 cell proliferation 108 0.295443831 cell recognition 9 0.382978723 cell redox homeostasis 1 2.025423729 cell surface receptor linked signal transduction 376 0.330721864 cell wall catabolism 2 0.474629162 cell-cell adhesion 91 0.282191781 cell-cell recognition 2 0.566591579 cell-cell signaling 206 0.338641335 cell-matrix adhesion 33 0.320675105 cell-mediated immune response 4 0.343793022 cellular biosynthesis 368 0.292565474 cellular carbohydrate catabolism 43 0.255591054 cellular carbohydrate metabolism 129 0.263929619 cellular catabolism 362 0.294174208 cellular defense response 18 0.269713904 cellular defense response (sensu Vertebrata) 4 0.343793022 cellular lipid catabolism 17 0.243150685 cellular lipid metabolism 222 0.284172532 cellular macromolecule catabolism 282 0.313589445 cellular macromolecule metabolism 1063 0.282666667 cellular metabolism 2333 0.288311688 cellular morphogenesis 79 0.28440367 cellular morphogenesis during differentiation 1 0.321637427 cellular nerve ensheathment 1 1.212328767 cellular physiological process 3657 0.292372881 cellular polysaccharide catabolism 6 0.323348313 cellular polysaccharide metabolism 24 0.297234444 cellular protein catabolism 235 0.314984709 cellular protein metabolism 947 0.283928571 cellular respiration 18 0.198394896 central nervous system development 21 0.38547486 chemosensory behavior 4 0.194834574 chemotaxis 22 0.341165815 chitin catabolism 1 0.657894737 chitin metabolism 2 0.492460882 chloride transport 24 0.285368955 cholesterol absorption 2 0.225507552 cholesterol biosynthesis 12 0.176421286 cholesterol catabolism 4 0.23965319 cholesterol metabolism 43 0.205882353 cholesterol transport 2 0.228255542 choline transport 1 0.564102564 chondroitin sulfate biosynthesis 1 0.3514377 chondroitin sulfate metabolism 1 0.3514377 chondroitin sulfate proteoglycan biosynthesis 3 0.3514377 "chondroitin sulfate proteoglycan biosynthesis\, polysaccharide chain biosynthesis " 2 0.289406028 chondroitin sulfate proteoglycan metabolism 3 0.3514377 chromatin assembly or disassembly 13 0.125899281 chromatin modification 59 0.27734375 chromatin silencing 3 0.830065359 chromatin-mediated maintenance of transcription 4 0.199369937 chromosome condensation 19 0.191082803 chromosome organization and biogenesis 99 0.255681818 chromosome organization and biogenesis (sensu Eukaryota) 81 0.261627907 chromosome segregation 28 0.207720888 ciliary or flagellar motility 1 0.280453258 circadian rhythm 8 0.213697782 circulation 46 0.307670127 citrate metabolism 3 0.115812918 citrate transport 1 0.105839416 coagulation 51 0.307692308 cobalamin transport 1 0.20735786 cocaine metabolism 1 0.085443038 coenzyme A biosynthesis 1 0.120588235 coenzyme A metabolism 3 0.120588235 coenzyme biosynthesis 9 0.417582418 coenzyme catabolism 14 0.144544582 coenzyme metabolism 35 0.248175182 cofactor biosynthesis 17 0.417582418 cofactor catabolism 23 0.14861461 cofactor metabolism 53 0.284416492 cofactor transport 8 0.233521175 collagen fibril organization 4 0.501256229 compound eye morphogenesis (sensu Endopterygota) 1 0.36682243 copper ion homeostasis 4 0.416638686 cortical actin cytoskeleton organization and biogenesis 4 0.257768519 cortical cytoskeleton organization and biogenesis 4 0.257768519 cotranslational protein-membrane targeting 1 0.274647887 creatine biosynthesis 1 0.11328125 creatine metabolism 1 0.11328125 cyclic nucleotide biosynthesis 20 0.301212246 cyclic nucleotide metabolism 22 0.262921909 cyclic-nucleotide-mediated signaling 34 0.33276921 cyclin catabolism 1 0.061818182 cyclooxygenase pathway 2 0.2454982 cysteine biosynthesis 2 0.346354794 cysteine metabolism 3 0.417582418 cytokine and chemokine mediated signaling pathway 3 0.166431594 cytokine biosynthesis 5 0.327272727 cytokine metabolism 5 0.327272727 cytokine production 8 0.290951178 cytokine secretion 3 0.211981567 cytokinesis 89 0.287179487 cytolysis 7 0.284394251 cytolysis of host cells 2 0.361850305 cytoplasm organization and biogenesis 32 0.282181596 cytoplasmic sequestering of protein 2 0.373233909 cytoplasmic sequestering of transcription factor 2 0.373233909 cytoskeletal anchoring 16 0.35063117 cytoskeleton organization and biogenesis 120 0.257270851 cytoskeleton-dependent intracellular transport 44 0.248120882 cytosol to ER transport 1 0.037453184 death 217 0.30749354 defense response 203 0.350931677 defense response to bacteria 4 0.325363033 defense response to pathogen 1 0.657894737 dendrite morphogenesis 1 0.865546218 deoxyribonucleoside diphosphate biosynthesis 1 0.236947791 deoxyribonucleoside diphosphate metabolism 1 0.236947791 deoxyribonucleoside metabolism 1 1.774647887 deoxyribonucleoside monophosphate biosynthesis 1 0.767857143 deoxyribonucleoside monophosphate metabolism 1 0.767857143 deoxyribonucleoside triphosphate metabolism 1 1.774647887 deoxyribonucleotide biosynthesis 2 0.502402467 deoxyribonucleotide catabolism 1 0.099190283 deoxyribonucleotide metabolism 4 0.502402467 dephosphorylation 13 0.470873786 dermatan sulfate metabolism 1 0.3514377 dermatan sulfate proteoglycan biosynthesis 3 0.3514377 dermatan sulfate proteoglycan metabolism 3 0.3514377 detection of abiotic stimulus 72 0.367680878 detection of chemical substance 5 0.199192957 detection of external stimulus 181 0.313901345 detection of light 13 0.657142857 detection of mechanical stimulus 54 0.369875724 detection of sound 1 0.515037594 detection of visible light 2 0.808571429 "determination of anterior/posterior axis\, embryo " 2 0.125946137 development of primary male sexual characteristics 4 0.558771307 development of primary sexual characteristics 7 0.205882353 "di-\, tri-valent inorganic cation homeostasis " 30 0.220972981 "di-\, tri-valent inorganic cation transport " 52 0.220650407 diacylglycerol biosynthesis 2 0.304403131 diacylglycerol metabolism 3 0.314285714 dicarboxylic acid transport 12 0.121684963 digestion 31 0.284416492 disaccharide catabolism 1 0.19112628 disaccharide metabolism 2 0.250521818 disruption of host cells 2 0.361850305 dissemination or transmission of an organism from a host 2 0.566591579 diuresis 4 0.429520344 dopamine receptor signaling pathway 1 0.094420601 "dopamine receptor\, adenylate cyclase inhibiting pathway " 1 0.094420601 double-strand break repair 6 0.443999561 double-strand break repair via nonhomologous end-joining 1 0.249122807 drug metabolism 3 0.474509804 drug transport 8 0.448028922 ear morphogenesis 3 0.115234375 ectoderm development 23 0.328571429 electron transport 145 0.351351351 embryonic appendage morphogenesis 3 0.36682243 embryonic axis specification 2 0.125946137 embryonic development 17 0.213740458 embryonic development (sensu Metazoa) 2 0.709826153 embryonic heart tube development 1 0.612244898 embryonic limb morphogenesis 3 0.36682243 embryonic morphogenesis 6 0.241028403 embryonic pattern specification 5 0.130434783 endocytosis 92 0.288636637 endoderm development 4 0.402677782 endosome organization and biogenesis 9 0.231527094 endosome to lysosome transport 1 0.709580838 endosome transport 9 0.231527094 energy derivation by oxidation of organic compounds 84 0.251490511 energy reserve metabolism 25 0.214634146 enhancement of virulence 2 0.566591579 entrainment of circadian clock 2 0.392764134 entry into host 7 0.371794872 entry into host cell 7 0.371794872 enzyme linked receptor protein signaling pathway 72 0.341927018 epidermal growth factor receptor signaling pathway 6 0.428515688 epidermis development 21 0.328571429 epithelial cell differentiation 1 0.742358079 epithelial cell proliferation 1 0.444444444 ergosterol biosynthesis 1 0.916666667 ergosterol metabolism 1 0.916666667 erythrocyte differentiation 1 0.56741573 establishment and/or maintenance of cell polarity 7 0.384615385 establishment and/or maintenance of chromatin architecture 71 0.262376238 establishment of RNA localization 12 0.223593952 establishment of localization 1059 0.296 establishment of protein localization 263 0.313901345 estrogen biosynthesis 4 0.189030969 estrogen catabolism 2 0.309620596 estrogen metabolism 8 0.189030969 ethanol metabolism 3 0.489361702 ethanol oxidation 3 0.489361702 excretion 21 0.312101911 exocytosis 20 0.241890441 extracellular matrix organization and biogenesis 18 0.365593017 extracellular structure organization and biogenesis 18 0.365593017 extracellular transport 1 0.676156584 eye morphogenesis 2 0.344229929 eye morphogenesis (sensu Endopterygota) 1 0.36682243 eye photoreceptor cell development 1 0.321637427 eye photoreceptor cell differentiation 1 0.321637427 eye pigment biosynthesis 1 0.470779221 eye pigment metabolism 1 0.470779221 eye pigmentation 1 0.470779221 eye-antennal disc development 1 0.36682243 eye-antennal disc metamorphosis 1 0.36682243 fat body development 1 0.522267206 fat cell differentiation 3 0.569230769 fat-soluble vitamin metabolism 9 0.179487179 fatty acid beta-oxidation 10 0.509433769 fatty acid biosynthesis 26 0.185309567 fatty acid catabolism 1 0.047619048 fatty acid desaturation 3 0.165158371 fatty acid metabolism 78 0.275786614 fatty acid oxidation 13 0.533519553 fatty acid transport 1 1 feeding behavior 5 0.343283582 female gamete generation 6 0.208827404 fertilization 14 0.345776281 fertilization (sensu Metazoa) 14 0.345776281 fibrinolysis 1 0.746666667 fibroblast growth factor receptor signaling pathway 4 0.448917138 filopodium formation 3 0.208108108 fluid secretion 7 0.312101911 fluid transport 3 0.764397906 focal adhesion formation 4 0.296366965 folic acid transport 4 0.364625 follicle-stimulating hormone secretion 1 0.703883495 formation of primary germ layer 1 0.807407407 frizzled signaling pathway 13 0.188 frizzled-2 signaling pathway 10 0.313197825 fructose metabolism 9 0.214634146 fucose metabolism 2 0.473180328 fusion of sperm to egg plasma membrane 1 0.211981567 galactolipid metabolism 1 0.243150685 galactose metabolism 3 0.174454829 gametogenesis 54 0.274661509 gas transport 4 0.326857143 gastrulation 1 0.807407407 gene silencing 4 0.653277194 generation of precursor metabolites and energy 225 0.314465409 germ cell development 4 0.528091474 germ cell migration 5 0.220095694 glial cell migration 1 0.807407407 gliogenesis 1 0.807407407 glucan biosynthesis 5 0.414364641 glucan catabolism 5 0.210714286 glucan metabolism 20 0.239078073 glucocorticoid metabolism 1 0.363636364 gluconeogenesis 13 0.290836653 glucosamine catabolism 1 0.657894737 glucosamine metabolism 4 0.341064534 glucose homeostasis 1 0.569230769 glucose metabolism 46 0.280366423 glucose transport 6 0.258615016 glucuronate metabolism 1 0.382978723 glutamate metabolism 3 0.417582418 glutamate signaling pathway 23 0.564831261 glutamine family amino acid biosynthesis 8 0.197433676 glutamine family amino acid catabolism 5 0.159468439 glutamine family amino acid metabolism 22 0.208608059 glutamine metabolism 15 0.20952381 glutathione biosynthesis 3 0.417582418 glutathione metabolism 3 0.417582418 glycerol catabolism 2 0.51127411 glycerol ether biosynthesis 3 0.314285714 glycerol ether catabolism 1 1.243055556 glycerol ether metabolism 10 0.356916506 glycerol metabolism 7 0.575581395 glycerol-3-phosphate metabolism 3 0.555555556 glycerolipid biosynthesis 3 0.314285714 glycerolipid catabolism 1 1.243055556 glycerolipid metabolism 10 0.356916506 glycerophospholipid biosynthesis 8 0.268280075 glycerophospholipid metabolism 12 0.268280075 glycine metabolism 4 0.259567267 glycogen biosynthesis 5 0.414364641 glycogen metabolism 20 0.239078073 glycolipid biosynthesis 4 0.2645909 glycolipid catabolism 3 0.243150685 glycolipid metabolism 11 0.260299625 glycolysis 22 0.253346188 glycoprotein biosynthesis 32 0.41573679 glycoprotein catabolism 5 0.496875 glycoprotein metabolism 39 0.422382671 glycosaminoglycan biosynthesis 7 0.371584699 glycosaminoglycan catabolism 6 0.143691939 glycosaminoglycan metabolism 21 0.336996337 glycoside catabolism 1 0.421800948 glycoside metabolism 1 0.421800948 glycosphingolipid biosynthesis 3 0.268882175 glycosphingolipid metabolism 9 0.268882175 glycosylceramide biosynthesis 1 0.091324201 glycosylceramide metabolism 2 0.167237443 glyoxylate cycle 3 0.071559633 glyoxylate metabolism 3 0.071559633 gonad development 7 0.205882353 group transfer coenzyme metabolism 4 0.162724673 growth 68 0.279562535 growth hormone secretion 1 0.336601307 heart development 16 0.274566547 heme biosynthesis 6 0.565174129 heme catabolism 4 1.786281478 heme metabolism 13 0.797014925 heme oxidation 3 0.385714286 heme transport 1 0.025761124 hemocyte development 5 0.246938776 hemocyte differentiation (sensu Arthropoda) 5 0.246938776 hemolysis 2 0.361850305 hemopoiesis 25 0.215469613 hemopoietic or lymphoid organ development 25 0.215469613 hemostasis 54 0.303099886 heparan sulfate proteoglycan biosynthesis 1 0.382978723 "heparan sulfate proteoglycan biosynthesis\, polysaccharide chain biosynthesis " 1 0.382978723 heparan sulfate proteoglycan metabolism 1 0.382978723 heparin metabolism 1 0.382978723 heterocycle metabolism 27 0.333333333 heterophilic cell adhesion 8 0.56750733 hexose biosynthesis 15 0.263929619 hexose catabolism 27 0.255591054 hexose metabolism 58 0.266912907 hexose transport 6 0.258615016 hindbrain development 2 1.069382498 histidine family amino acid biosynthesis 1 0.174050633 histidine family amino acid catabolism 2 0.503003547 histidine family amino acid metabolism 5 0.365 histidine metabolism 5 0.365 histogenesis 60 0.297491616 histone mRNA 3'-end processing 1 0.673239437 histone mRNA metabolism 1 0.673239437 histone modification 13 0.403773585 histone phosphorylation 1 0.403773585 homeostasis 52 0.291811687 homophilic cell adhesion 66 0.254129129 hormone biosynthesis 8 0.206795221 hormone catabolism 3 0.204359673 hormone metabolism 22 0.285726765 hormone secretion 8 0.441083813 hormone-mediated signaling 4 0.111905632 humoral defense mechanism (sensu Vertebrata) 18 0.253808978 humoral immune response 26 0.238921958 hyaluronan metabolism 3 0.361867704 hydrogen ion homeostasis 9 0.248878924 hydrogen transport 25 0.211981567 hyperphosphorylation 1 0.452054795 icosanoid biosynthesis 7 0.394957983 icosanoid metabolism 13 0.331491713 imaginal disc development 1 0.36682243 imaginal disc metamorphosis 1 0.36682243 immune cell activation 21 0.257575758 immune cell chemotaxis 3 0.37254902 immune cell migration 3 0.37254902 immune response 189 0.335978836 inactivation of MAPK 3 0.287066246 indolalkylamine biosynthesis 3 0.485074627 indolalkylamine catabolism 2 0.664761198 indolalkylamine metabolism 5 0.485074627 indole and derivative metabolism 5 0.485074627 indole derivative biosynthesis 3 0.485074627 indole derivative catabolism 2 0.664761198 indole derivative metabolism 5 0.485074627 induction of apoptosis 51 0.242165242 induction of programmed cell death 51 0.242165242 inflammatory response 58 0.29709314 initiation of viral infection 7 0.371794872 innate immune response 2 0.432943746 inner ear morphogenesis 3 0.115234375 inner mitochondrial membrane organization and biogenesis 1 0.232 inorganic anion transport 74 0.379541735 insulin receptor signaling pathway 1 0.972222222 insulin secretion 6 0.441083813 interaction between organisms 14 0.271943961 intercellular junction assembly 9 0.270935961 intercellular junction assembly and/or maintenance 9 0.270935961 interferon-gamma biosynthesis 1 0.360313316 interleukin-1 beta secretion 2 0.376189017 interleukin-1 secretion 2 0.376189017 interleukin-10 biosynthesis 1 0.25462963 interleukin-13 biosynthesis 1 0.25462963 interleukin-2 biosynthesis 3 0.327272727 interleukin-4 biosynthesis 1 0.25462963 interleukin-6 biosynthesis 1 0.113402062 intermediate filament cytoskeleton organization and biogenesis 1 0.384615385 intermediate filament-based process 1 0.384615385 interphase 22 0.261363637 interphase of mitotic cell cycle 22 0.261363637 intestinal absorption 2 0.225507552 intra-Golgi transport 16 0.31261062 intracellular protein transport 158 0.303846154 intracellular signaling cascade 393 0.310195228 intracellular transport 262 0.27634885 intracellular virion transport 2 0.566591579 ion channel clustering 1 0.425925926 ion homeostasis 45 0.248878924 ion transport 331 0.302238806 ionic insulation of neurons by glial cells 1 1.212328767 iron ion homeostasis 10 0.267374182 isocitrate metabolism 2 0.095935804 isoprenoid biosynthesis 5 0.188908146 isoprenoid metabolism 6 0.260307732 keratan sulfate metabolism 1 0.174454829 keratinocyte differentiation 5 0.303921569 kidney development 1 0.807407407 killing of host cells 2 0.361850305 lactate transport 1 0.45177665 lactation 1 0.105058366 larval or pupal development (sensu Insecta) 1 0.36682243 latent virus infection 1 0.110410095 learning and/or memory 11 0.452054795 leucine metabolism 2 0.118189369 leukocyte adhesion 4 0.372171946 leukotriene biosynthesis 4 0.557432695 leukotriene metabolism 5 0.394957983 limb morphogenesis 3 0.36682243 lipid biosynthesis 80 0.261462944 lipid catabolism 43 0.305555556 lipid digestion 2 0.225507552 lipid glycosylation 1 0.414634146 lipid metabolism 288 0.29247715 lipid modification 13 0.419753086 lipid raft polarization 1 1.212328767 lipid transport 30 0.293798027 lipopolysaccharide biosynthesis 2 0.307916284 lipopolysaccharide metabolism 2 0.307916284 lipoprotein biosynthesis 10 0.259758772 lipoprotein metabolism 13 0.283928571 lipoprotein transport 1 0.03960396 localization 1062 0.296014441 locomotion 121 0.303921569 locomotory behavior 124 0.306506239 long-term memory 1 0.141666667 lung development 1 0.259493671 lymphocyte activation 17 0.259493671 lymphocyte chemotaxis 1 0.475770925 lymphocyte differentiation 10 0.17999531 lymphocyte proliferation 5 0.360313316 lysine metabolism 1 0.441416894 lysosomal transport 2 0.65416346 lysosome organization and biogenesis 2 0.65416346 mRNA 3'-end processing 5 0.065060241 mRNA catabolism 1 0.341818182 mRNA cleavage 5 0.065060241 mRNA editing 1 0.103030303 mRNA metabolism 46 0.207688102 mRNA modification 1 0.103030303 mRNA processing 39 0.192307692 mRNA transport 10 0.204840621 mRNA-nucleus export 10 0.204840621 macroautophagy 1 0.394117647 macromolecule biosynthesis 227 0.287066246 macromolecule catabolism 286 0.313589445 macromolecule metabolism 1144 0.282448316 macrophage activation 1 0.113402062 macrophage differentiation 1 0.908450704 main pathways of carbohydrate metabolism 51 0.248175182 maintenance of fidelity during DNA-dependent DNA replication 7 0.345360825 maintenance of localization 4 0.373233909 maintenance of protein localization 4 0.373233909 malate metabolism 2 0.42399734 male gamete generation 40 0.272355843 male gonad development 4 0.558771307 male meiosis 2 0.181432518 male sex differentiation 4 0.558771307 mannose metabolism 4 0.326948052 mechanosensory behavior 2 0.522941301 meiosis 23 0.253424658 meiosis I 12 0.252902805 meiotic cell cycle 23 0.253424658 meiotic recombination 9 0.297491039 melanin metabolism 1 0.171296296 melanocyte differentiation 1 0.756578947 melatonin biosynthesis 3 0.485074627 melatonin metabolism 3 0.485074627 membrane fusion 13 0.363057325 membrane lipid biosynthesis 16 0.256465602 membrane lipid catabolism 8 0.268634166 membrane lipid metabolism 48 0.282843137 membrane organization and biogenesis 6 0.170006969 memory 1 0.141666667 mesoderm development 12 0.290296496 mesoderm formation 1 0.807407407 mesoderm migration 1 0.807407407 mesoderm morphogenesis 1 0.807407407 metabolic compound salvage 4 0.466628551 metabolism 2537 0.287066246 metabotropic glutamate receptor signaling pathway 10 0.422326103 "metabotropic glutamate receptor\, phospholipase C activating pathway " 2 0.449037023 metal ion homeostasis 32 0.220972981 metal ion transport 169 0.261455526 metamorphosis 1 0.36682243 metamorphosis (sensu Insecta) 1 0.36682243 metanephros development 1 0.807407407 methionine biosynthesis 5 0.264094955 methionine metabolism 7 0.318996416 mevalonate transport 2 0.514086008 microspike biogenesis 5 0.208108108 microtubule cytoskeleton organization and biogenesis 22 0.260600031 microtubule depolymerization 4 0.21784356 microtubule-based movement 44 0.248120882 microtubule-based process 69 0.244604317 mismatch repair 7 0.345360825 mitochondrial citrate transport 1 0.105839416 mitochondrial fission 1 0.232 mitochondrial fusion 3 0.232 mitochondrial membrane organization and biogenesis 4 0.086474501 mitochondrial transport 14 0.187668245 mitochondrion organization and biogenesis 6 0.092011719 mitosis 84 0.260289171 mitotic anaphase 4 0.291457475 mitotic cell cycle 105 0.25 mitotic checkpoint 3 0.92 mitotic chromosome condensation 19 0.191082803 mitotic metaphase/anaphase transition 3 0.326086957 mitotic recombination 2 0.344331507 mitotic sister chromatid segregation 19 0.191082803 mitotic spindle organization and biogenesis 3 0.387387387 modification of host morphology or physiology 2 0.361850305 monoamine transport 1 0.425925926 monocarboxylic acid transport 9 0.295 monocyte differentiation 3 0.56741573 monosaccharide biosynthesis 15 0.263929619 monosaccharide catabolism 28 0.262743624 monosaccharide metabolism 59 0.269896194 monosaccharide transport 6 0.258615016 monovalent inorganic cation homeostasis 11 0.248878924 monovalent inorganic cation transport 143 0.261455526 morphogenesis 531 0.301829268 morphogenesis of an epithelium 1 0.742358079 motor axon guidance 1 0.807407407 multidrug transport 4 0.298178282 muscle cell differentiation 5 0.327272727 muscle contraction 79 0.234567901 muscle development 81 0.259036145 mutagenesis 1 0.415300546 myelination 1 1.212328767 myeloid cell differentiation 3 0.56741573 myoblast differentiation 2 0.252873563 myoblast fusion 1 0.234567901 myogenesis 11 0.407665505 mystery cell fate differentiation (sensu Endopterygota) 1 0.36682243 natriuresis 4 0.429520344 natural killer cell activation 1 0.360313316 negative regulation of JAK-STAT cascade 1 0.287066246 negative regulation of S phase of mitotic cell cycle 3 0.198830409 negative regulation of T cell activation 2 0.165967068 negative regulation of T cell differentiation 2 0.165967068 negative regulation of T-helper cell differentiation 2 0.165967068 negative regulation of adenylate cyclase activity 9 0.369747899 negative regulation of amino acid metabolism 1 0.287066246 negative regulation of apoptosis 31 0.301886792 negative regulation of biological process 97 0.251356239 negative regulation of biosynthesis 1 0.091324201 negative regulation of blood coagulation 1 0.746666667 negative regulation of catabolism 1 0.512727273 negative regulation of cell activation 2 0.165967068 negative regulation of cell cycle 5 0.145695364 negative regulation of cell differentiation 2 0.165967068 negative regulation of cell organization and biogenesis 3 0.191082803 negative regulation of cellular biosynthesis 1 0.091324201 negative regulation of cellular metabolism 42 0.219435929 negative regulation of cellular physiological process 83 0.236619718 negative regulation of cellular process 85 0.240740741 negative regulation of coagulation 1 0.746666667 negative regulation of cyclase activity 9 0.369747899 negative regulation of cyclin dependent protein kinase activity 2 0.105753415 negative regulation of development 3 0.164251208 negative regulation of enzyme activity 11 0.301775148 negative regulation of follicle-stimulating hormone secretion 1 0.703883495 "negative regulation of gene expression\, epigenetic " 3 0.830065359 negative regulation of glucosylceramide biosynthesis 1 0.091324201 negative regulation of growth 1 0.132653061 negative regulation of hormone secretion 1 0.703883495 negative regulation of immune response 2 0.165967068 negative regulation of insulin receptor signaling pathway 1 0.972222222 negative regulation of lipid biosynthesis 1 0.091324201 negative regulation of lipid metabolism 1 0.091324201 negative regulation of lyase activity 9 0.369747899 negative regulation of lymphocyte activation 2 0.165967068 negative regulation of lymphocyte differentiation 2 0.165967068 negative regulation of metabolism 45 0.210300429 negative regulation of microtubule depolymerization 3 0.191082803 negative regulation of microtubule polymerization or depolymerization 3 0.191082803 negative regulation of mitotic cell cycle 3 0.198830409 "negative regulation of nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism " 39 0.210300429 negative regulation of nucleocytoplasmic transport 2 0.373233909 negative regulation of organismal physiological process 2 0.165967068 negative regulation of peptidyl-tyrosine phosphorylation 1 0.287066246 negative regulation of phosphate metabolism 1 0.287066246 negative regulation of phosphorylation 1 0.287066246 negative regulation of physiological process 85 0.240740741 negative regulation of programmed cell death 31 0.301886792 negative regulation of protein amino acid phosphorylation 1 0.287066246 negative regulation of protein catabolism 1 0.512727273 negative regulation of protein kinase activity 2 0.105753415 negative regulation of protein metabolism 5 0.287066246 negative regulation of protein transport 2 0.373233909 negative regulation of protein-nucleus import 2 0.373233909 negative regulation of proteolysis and peptidolysis 1 0.512727273 negative regulation of secretion 1 0.703883495 negative regulation of signal transduction 2 0.629644234 negative regulation of sister chromatid cohesion 1 0.489711934 negative regulation of transcription 39 0.210300429 negative regulation of transferase activity 2 0.105753415 negative regulation of translation 3 0.225806452 negative regulation of transport 2 0.373233909 negative regulation of tyrosine phosphorylation of STAT protein 1 0.287066246 negative regulation of tyrosine phosphorylation of Stat3 protein 1 0.287066246 negative regulation of viral genome replication 1 0.139393939 negative regulation of viral life cycle 1 0.139393939 nerve ensheathment 3 1.212328767 nerve maturation 3 1.212328767 neurite morphogenesis 31 0.325242718 neurogenesis 173 0.312977099 neuron adhesion 4 0.961409396 neuron differentiation 2 0.508199195 neuron lineage restriction 2 0.321420869 neuron migration 1 0.219839142 neuron recognition 4 0.532832833 neuron remodeling 1 1.575757576 neuropeptide signaling pathway 28 0.351844958 neurophysiological process 284 0.343771405 neurotransmitter biosynthesis 2 0.206993819 neurotransmitter catabolism 4 0.219055556 neurotransmitter metabolism 8 0.206993819 neurotransmitter secretion 8 0.469683567 neurotransmitter transport 30 0.344832299 neurotransmitter uptake 8 0.334332085 neutral amino acid transport 5 0.586956522 neutral lipid biosynthesis 3 0.314285714 neutral lipid catabolism 1 1.243055556 neutral lipid metabolism 10 0.356916506 neutrophil activation 1 0.153310105 neutrophil chemotaxis 2 0.328476345 nicotinamide metabolism 5 0.285077951 nitric oxide biosynthesis 5 0.351351351 nitric oxide metabolism 5 0.351351351 nitrogen compound biosynthesis 2 0.123770253 nitrogen compound catabolism 3 0.159468439 nitrogen compound metabolism 14 0.187602499 non-recombinational repair 1 0.249122807 nuclear export 14 0.21078179 nuclear import 16 0.328414306 "nuclear mRNA splicing\, via spliceosome " 5 0.264631043 nuclear transport 30 0.255007167 nucleic acid transport 12 0.223593952 nucleobase biosynthesis 3 0.08707124 nucleobase metabolism 4 0.147381774 nucleobase transport 4 0.501424501 "nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism " 890 0.286390266 "nucleobase\, nucleoside\, nucleotide and nucleic acid transport " 18 0.240700019 nucleocytoplasmic transport 35 0.258461538 nucleoside biosynthesis 1 0.081325301 nucleoside diphosphate biosynthesis 1 0.236947791 nucleoside diphosphate catabolism 1 0.084158416 nucleoside diphosphate metabolism 2 0.160553104 nucleoside metabolism 12 0.380067056 nucleoside monophosphate biosynthesis 12 0.366465517 nucleoside monophosphate catabolism 2 0.533266424 nucleoside monophosphate metabolism 12 0.366465517 nucleoside phosphate metabolism 1 0.452513966 nucleoside salvage 4 0.466628551 nucleoside transport 2 0.352193508 nucleoside triphosphate biosynthesis 8 0.505784542 nucleoside triphosphate catabolism 2 0.160173338 nucleoside triphosphate metabolism 12 0.394398576 nucleosome assembly 8 0.134561399 nucleosome disassembly 2 0.087917261 nucleotide biosynthesis 48 0.337611598 nucleotide catabolism 8 0.160173338 nucleotide metabolism 72 0.298340482 nucleotide phosphorylation 1 1.462264151 nucleotide-excision repair 14 0.32529848 "nucleotide-excision repair\, DNA incision\, 5'-to lesion " 1 0.468581688 nucleotide-sugar biosynthesis 1 0.071340713 nucleotide-sugar metabolism 4 0.261899216 nucleotide-sugar transport 2 0.355975528 nutrient import 2 0.622939694 odontogenesis 1 0.198391421 oligopeptide transport 5 0.418918919 oligosaccharide biosynthesis 2 0.363937979 oligosaccharide metabolism 6 0.241052068 one-carbon compound metabolism 20 0.30568789 oocyte axis determination 2 0.238517643 oocyte construction 2 0.238517643 organ development 433 0.304597701 organelle fission 1 0.232 organelle fusion 3 0.232 organelle organization and biogenesis 256 0.256323881 organic acid biosynthesis 27 0.18707483 organic acid catabolism 1 0.047619048 organic acid metabolism 209 0.264094955 organic acid transport 56 0.249974648 organic anion transport 13 0.264957265 organic cation transport 4 0.266384494 organismal physiological process 680 0.310999445 organogenesis 415 0.30952381 ossification 11 0.201954397 osteoclast differentiation 1 0.079365079 oxidative phosphorylation 7 0.322916667 oxidoreduction coenzyme metabolism 8 0.414761198 oxygen and reactive oxygen species metabolism 30 0.412589134 oxygen transport 4 0.326857143 pancreatic juice secretion 2 0.225507552 paranodal junction formation 2 1.15125 parturition 2 0.302349604 pathogenesis 7 0.371794872 pattern specification 10 0.17208762 pentose catabolism 1 0.854166667 pentose metabolism 1 0.854166667 pentose-phosphate shunt 4 0.37016915 peptide antigen stabilization 1 0.282051282 peptide antigen transport 2 0.566591579 peptide cross-linking 6 0.25308088 peptide hormone processing 2 0.449640968 peptide hormone secretion 6 0.441083813 peptide metabolism 4 0.242149237 peptide stabilization 1 0.282051282 peptide transport 8 0.395356895 peptidoglycan catabolism 1 0.275574113 peptidoglycan metabolism 2 0.237787057 peptidyl-amino acid modification 6 0.324967722 peptidyl-diphthamide biosynthesis from peptidyl-histidine 1 0.362869198 peptidyl-histidine modification 1 0.362869198 peptidyl-tyrosine modification 4 0.402792383 peptidyl-tyrosine phosphorylation 2 0.285734958 peptidyl-tyrosine sulfation 2 0.560072268 perception of smell 7 0.303867403 perception of sound 53 0.368539326 perception of sweet taste 1 0.523584906 perception of taste 2 0.461792453 perception of umami taste 1 0.4 peroxisomal membrane transport 1 0.369230769 peroxisome division 2 0.144031091 peroxisome organization and biogenesis 2 0.144031091 phagocytosis 11 0.183486239 "phagocytosis\, engulfment " 1 1.077235772 "phagocytosis\, recognition " 1 0.123529412 phenol metabolism 8 0.326289018 phosphagen biosynthesis 1 0.11328125 phosphagen metabolism 1 0.11328125 phosphate metabolism 55 0.318681319 phosphate transport 47 0.421052632 phosphoenolpyruvate-dependent sugar phosphotransferase system 1 0.343558282 phosphoinositide-mediated signaling 35 0.314285714 phospholipase C activation 4 0.239801311 phospholipid biosynthesis 12 0.244110276 phospholipid catabolism 3 0.108731466 phospholipid dephosphorylation 12 0.445313436 phospholipid metabolism 29 0.283928571 phosphorus metabolism 55 0.318681319 phosphorylation 28 0.269364465 photoreceptor cell development 1 0.321637427 photoreceptor cell differentiation 1 0.321637427 photoreceptor maintenance 4 0.428335618 phototransduction 11 0.310580205 pigment biosynthesis 7 0.470779221 pigment catabolism 4 1.786281478 pigment cell differentiation 1 0.756578947 pigment metabolism 15 0.470779221 pigmentation 1 0.470779221 pinocytosis 4 0.787275837 plasma membrane fusion 1 0.211981567 plasma membrane organization and biogenesis 1 1.212328767 platelet activation 2 1.15125 polyamine biosynthesis 3 0.417647059 polyamine metabolism 3 0.417647059 polyisoprenoid biosynthesis 1 0.188908146 polyisoprenoid metabolism 2 0.260307732 polyol catabolism 2 0.51127411 polyol metabolism 7 0.575581395 polyol transport 2 0.622939694 polyphosphate metabolism 1 0.201954397 polysaccharide biosynthesis 8 0.399909593 polysaccharide catabolism 6 0.323348313 polysaccharide metabolism 27 0.26744186 porphyrin biosynthesis 8 0.565174129 porphyrin catabolism 9 0.385714286 porphyrin metabolism 17 0.385714286 positive regulation of I-kappaB kinase/NF-kappaB cascade 45 0.31641791 positive regulation of Ras protein signal transduction 1 0.137472284 positive regulation of T cell activation 3 0.167682927 positive regulation of T cell differentiation 2 0.165967068 positive regulation of T cell proliferation 1 0.360313316 positive regulation of T-helper cell differentiation 2 0.165967068 positive regulation of adenylate cyclase activity 5 0.244939271 positive regulation of apoptosis 51 0.242165242 positive regulation of biological process 152 0.277675901 positive regulation of biosynthesis 7 0.25462963 positive regulation of caspase activity 6 0.389180402 positive regulation of cell activation 4 0.263998122 positive regulation of cell cycle 1 0.489711934 positive regulation of cell differentiation 3 0.167682927 positive regulation of cell proliferation 2 0.40237888 positive regulation of cellular biosynthesis 6 0.290951178 positive regulation of cellular metabolism 22 0.212173626 positive regulation of cellular physiological process 75 0.242165242 positive regulation of cellular process 120 0.285324168 positive regulation of cholesterol biosynthesis 1 0.091324201 positive regulation of cyclase activity 5 0.244939271 positive regulation of cytokine biosynthesis 5 0.327272727 positive regulation of cytokine production 7 0.327272727 positive regulation of cytokine secretion 2 0.376189017 positive regulation of cytosolic calcium ion concentration 12 0.310600647 positive regulation of development 3 0.167682927 positive regulation of endocytosis 1 0.444444444 positive regulation of enzyme activity 37 0.244939271 positive regulation of epithelial cell proliferation 1 0.444444444 "positive regulation of gene expression\, epigenetic " 4 0.199369937 positive regulation of hydrolase activity 6 0.389180402 positive regulation of immune response 10 0.290951178 positive regulation of interleukin-1 secretion 2 0.376189017 positive regulation of lipid biosynthesis 1 0.091324201 positive regulation of lipid metabolism 1 0.091324201 positive regulation of lyase activity 5 0.244939271 positive regulation of lymphocyte activation 4 0.263998122 positive regulation of lymphocyte differentiation 2 0.165967068 positive regulation of lymphocyte proliferation 2 0.40237888 positive regulation of metabolism 23 0.210300429 positive regulation of mitosis 1 0.489711934 positive regulation of mitotic metaphase/anaphase transition 1 0.489711934 positive regulation of monocyte differentiation 1 0.56741573 positive regulation of myeloid cell differentiation 1 0.56741573 positive regulation of nitric oxide biosynthesis 1 0.063439065 "positive regulation of nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism " 16 0.196335625 positive regulation of organismal physiological process 10 0.290951178 positive regulation of physiological process 78 0.238898713 positive regulation of programmed cell death 51 0.242165242 positive regulation of protein biosynthesis 5 0.327272727 positive regulation of protein kinase activity 27 0.272058824 positive regulation of protein metabolism 5 0.327272727 positive regulation of protein secretion 2 0.376189017 positive regulation of receptor mediated endocytosis 1 0.444444444 positive regulation of secretion 2 0.376189017 positive regulation of signal transduction 47 0.31641791 positive regulation of small GTPase mediated signal transduction 1 0.137472284 positive regulation of steroid metabolism 1 0.091324201 positive regulation of transcription 16 0.196335625 positive regulation of transferase activity 27 0.272058824 positive regulation of transforming growth factor beta receptor signaling pathway 1 0.074879227 positive regulation of transport 1 0.444444444 positive regulation of urothelial cell proliferation 1 0.444444444 positive regulation of vascular endothelial growth factor receptor signaling pathway 1 1.040816327 post-Golgi transport 5 0.231527094 post-embryonic development 2 0.343537415 postreplication repair 1 0.108196721 posttranscriptional gene silencing 1 0.251101322 potassium ion transport 80 0.297052473 pregnancy 20 0.395035792 prenylcysteine metabolism 1 0.094684385 primary metabolism 2237 0.283819629 programmed cell death 198 0.311886305 proline metabolism 5 0.187175043 prostanoid biosynthesis 3 0.303921569 prostanoid metabolism 5 0.303921569 prostate gland development 1 0.240740741 protein amino acid acetylation 6 0.258661137 protein amino acid alkylation 7 0.378181818 protein amino acid deacetylation 7 0.463114754 protein amino acid glycosylation 31 0.422382671 protein amino acid phosphorylation 11 0.247787611 protein amino acid sulfation 3 0.518518519 protein biosynthesis 192 0.282140624 protein catabolism 239 0.314984709 protein complex assembly 84 0.273844365 protein complex disassembly 2 0.087917261 protein depolymerization 4 0.21784356 protein folding 97 0.251141553 protein homooligomerization 7 0.142857143 protein import 16 0.328414306 protein insertion into membrane 1 0.4 protein kinase C activation 15 0.314285714 protein kinase cascade 129 0.301282051 protein lipidation 10 0.259758772 protein localization 267 0.313901345 protein metabolism 956 0.283950617 protein modification 390 0.283939594 protein oligomerization 8 0.284391535 protein polymerization 15 0.153310105 protein processing 11 0.287037037 protein repair 2 0.551687764 protein secretion 10 0.297902369 protein stabilization 6 0.334329569 protein targeting 47 0.364764268 protein tetramerization 3 0.124293785 protein transport 262 0.312391087 protein-ER retention 2 0.60777881 protein-ER targeting 1 0.274647887 protein-chromophore linkage 4 0.536960636 protein-cofactor linkage 2 0.14169378 protein-membrane targeting 6 0.334382767 protein-mitochondrial targeting 7 0.42020202 protein-nucleus export 3 0.2043222 protein-nucleus import 16 0.328414306 "protein-nucleus import\, docking " 7 0.416666667 protein-vacuolar targeting 1 0.394117647 proteoglycan biosynthesis 4 0.367208212 proteoglycan metabolism 5 0.382978723 proteolysis and peptidolysis 235 0.314984709 proton transport 25 0.211981567 purine base biosynthesis 2 0.05754424 purine base metabolism 3 0.08707124 purine base salvage 1 0.512027491 purine deoxyribonucleotide biosynthesis 1 0.236947791 purine deoxyribonucleotide metabolism 1 0.236947791 purine nucleoside biosynthesis 1 0.081325301 purine nucleoside diphosphate biosynthesis 1 0.236947791 purine nucleoside diphosphate metabolism 1 0.236947791 purine nucleoside metabolism 5 0.455645161 purine nucleoside monophosphate biosynthesis 11 0.337931034 purine nucleoside monophosphate catabolism 2 0.533266424 purine nucleoside monophosphate metabolism 11 0.337931034 purine nucleoside triphosphate biosynthesis 8 0.505784542 purine nucleoside triphosphate catabolism 2 0.160173338 purine nucleoside triphosphate metabolism 11 0.336283186 purine nucleotide biosynthesis 23 0.337931034 purine nucleotide catabolism 4 0.299930556 purine nucleotide metabolism 25 0.336283186 purine ribonucleoside biosynthesis 1 0.081325301 purine ribonucleoside metabolism 5 0.455645161 purine ribonucleoside salvage 4 0.466628551 purine ribonucleotide biosynthesis 19 0.395 purine ribonucleotide catabolism 4 0.299930556 purine ribonucleotide metabolism 21 0.337931034 purine salvage 4 0.466628551 purine transport 2 0.622939694 putrescine metabolism 1 0.53699284 pyridine nucleotide biosynthesis 1 0.285077951 pyridine nucleotide metabolism 5 0.285077951 pyridoxine metabolism 1 0.375 pyrimidine base biosynthesis 1 0.207692308 pyrimidine base metabolism 1 0.207692308 pyrimidine deoxyribonucleoside metabolism 1 1.774647887 pyrimidine deoxyribonucleotide biosynthesis 1 0.767857143 pyrimidine deoxyribonucleotide metabolism 2 1.271252515 pyrimidine nucleoside diphosphate catabolism 1 0.084158416 pyrimidine nucleoside diphosphate metabolism 1 0.084158416 pyrimidine nucleoside metabolism 2 0.995657277 pyrimidine nucleoside monophosphate biosynthesis 1 0.767857143 pyrimidine nucleoside monophosphate metabolism 1 0.767857143 pyrimidine nucleoside triphosphate metabolism 7 0.882086168 pyrimidine nucleotide biosynthesis 7 0.767857143 pyrimidine nucleotide catabolism 1 0.084158416 pyrimidine nucleotide metabolism 9 0.767857143 pyrimidine nucleotide-sugar transport 1 0.356687898 pyrimidine ribonucleoside metabolism 1 0.216666667 pyrimidine ribonucleotide biosynthesis 6 0.720570643 pyrimidine ribonucleotide catabolism 1 0.084158416 pyrimidine ribonucleotide metabolism 7 0.559055118 pyrimidine transport 2 0.622939694 pyruvate transport 3 0.25433526 queuosine biosynthesis 1 0.081325301 quinone cofactor biosynthesis 3 0.544444444 quinone cofactor metabolism 3 0.544444444 rRNA metabolism 15 0.4 rRNA processing 15 0.4 rRNA transcription 3 0.384313725 re-entry into mitotic cell cycle 1 0.1015625 reactivation of latent virus 1 0.110410095 receptor mediated endocytosis 14 0.340164056 regional subdivision 2 0.125946137 regulated secretory pathway 8 0.469683567 regulation of DNA metabolism 9 0.255681818 regulation of DNA recombination 2 0.146341807 regulation of DNA repair 3 0.341563786 regulation of DNA replication 1 0.287066246 regulation of G-protein coupled receptor protein signaling pathway 20 0.340242165 regulation of GTPase activity 18 0.326822468 regulation of I-kappaB kinase/NF-kappaB cascade 46 0.313306569 regulation of JAK-STAT cascade 1 0.287066246 regulation of JNK cascade 3 0.634204276 regulation of RNA metabolism 1 0.111538462 regulation of Ras protein signal transduction 1 0.137472284 regulation of S phase of mitotic cell cycle 3 0.198830409 regulation of T cell activation 3 0.167682927 regulation of T cell differentiation 2 0.165967068 regulation of T cell proliferation 1 0.360313316 regulation of T-helper 1 cell differentiation 2 0.165967068 regulation of T-helper 2 cell differentiation 2 0.165967068 regulation of T-helper cell differentiation 2 0.165967068 regulation of action potential 1 1.212328767 regulation of activated T cell proliferation 1 0.360313316 regulation of adenylate cyclase activity 14 0.335761524 regulation of amino acid metabolism 2 0.285734958 regulation of angiogenesis 1 0.746666667 regulation of apoptosis 91 0.254237288 regulation of axon extension 1 0.219839142 regulation of axonogenesis 1 0.219839142 regulation of behavior 11 0.328571429 regulation of biosynthesis 28 0.219202438 regulation of blood coagulation 1 0.746666667 regulation of blood pressure 17 0.303921569 regulation of blood vessel size 5 0.546938776 regulation of body fluids 64 0.311692249 regulation of body size 1 0.155172414 regulation of caspase activity 6 0.389180402 regulation of catabolism 2 0.503490074 regulation of cell activation 4 0.263998122 regulation of cell adhesion 11 0.287066246 regulation of cell cycle 168 0.285508432 regulation of cell differentiation 3 0.167682927 regulation of cell growth 41 0.272058824 regulation of cell migration 11 0.328571429 regulation of cell motility 11 0.328571429 regulation of cell organization and biogenesis 6 0.195978082 regulation of cell proliferation 2 0.40237888 regulation of cell shape 7 0.272058824 regulation of cell size 56 0.292480862 regulation of cell volume 2 0.2156282 regulation of cellular biosynthesis 27 0.225806452 regulation of cellular metabolism 187 0.23655914 regulation of cellular physiological process 472 0.262209314 regulation of cellular process 536 0.281517439 regulation of cholesterol biosynthesis 1 0.091324201 regulation of chromatin assembly or disassembly 3 0.200873362 regulation of circadian rhythm 1 0.763341067 regulation of coagulation 1 0.746666667 regulation of cyclase activity 14 0.335761524 regulation of cyclin dependent protein kinase activity 15 0.25 regulation of cytokine biosynthesis 5 0.327272727 regulation of cytokine production 7 0.327272727 regulation of cytokine secretion 2 0.376189017 regulation of development 50 0.26506167 regulation of endocytosis 5 0.444444444 regulation of enzyme activity 79 0.272727273 regulation of epithelial cell proliferation 1 0.444444444 regulation of exit from mitosis 2 0.215900622 regulation of exocytosis 3 0.092664093 regulation of eye photoreceptor cell development 1 0.321637427 regulation of follicle-stimulating hormone secretion 1 0.703883495 regulation of fusion of sperm to egg plasma membrane 1 0.211981567 "regulation of gene expression\, epigenetic " 21 0.317708333 regulation of glucosylceramide biosynthesis 1 0.091324201 regulation of glycolysis 1 0.494252874 regulation of growth 45 0.272058824 regulation of growth rate 1 0.90234375 regulation of hormone secretion 5 0.502392344 regulation of hydrolase activity 24 0.326822468 regulation of immune response 10 0.290951178 regulation of insulin receptor signaling pathway 1 0.972222222 regulation of insulin secretion 3 0.502392344 regulation of interferon-gamma biosynthesis 1 0.360313316 regulation of interleukin-1 beta secretion 2 0.376189017 regulation of interleukin-1 secretion 2 0.376189017 regulation of interleukin-10 biosynthesis 1 0.25462963 regulation of interleukin-13 biosynthesis 1 0.25462963 regulation of interleukin-2 biosynthesis 3 0.327272727 regulation of interleukin-4 biosynthesis 1 0.25462963 regulation of interleukin-6 biosynthesis 1 0.113402062 regulation of ion transport 2 0.171340328 regulation of lipid biosynthesis 1 0.091324201 regulation of lipid metabolism 3 0.516358464 regulation of locomotion 11 0.328571429 regulation of long-term neuronal synaptic plasticity 1 0.452054795 regulation of lyase activity 14 0.335761524 regulation of lymphocyte activation 4 0.263998122 regulation of lymphocyte differentiation 2 0.165967068 regulation of lymphocyte proliferation 2 0.40237888 regulation of mRNA processing 1 0.111538462 regulation of metabolism 194 0.238649941 regulation of microtubule depolymerization 3 0.191082803 regulation of microtubule polymerization or depolymerization 3 0.191082803 regulation of mitosis 15 0.482517483 regulation of mitotic cell cycle 3 0.198830409 regulation of mitotic metaphase/anaphase transition 3 0.326086957 regulation of monocyte differentiation 1 0.56741573 regulation of myeloid cell differentiation 1 0.56741573 regulation of neurogenesis 2 0.335946969 regulation of neuronal synaptic plasticity 1 0.452054795 regulation of neurotransmitter levels 21 0.351758794 regulation of nitric oxide biosynthesis 1 0.063439065 "regulation of nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism " 161 0.240740741 regulation of nucleocytoplasmic transport 2 0.373233909 regulation of organismal physiological process 14 0.319687319 regulation of peptidyl-tyrosine phosphorylation 2 0.285734958 regulation of phosphate metabolism 2 0.285734958 regulation of phosphorus metabolism 2 0.285734958 regulation of phosphorylation 2 0.285734958 regulation of physiological process 489 0.266791045 regulation of programmed cell death 91 0.254237288 regulation of protein amino acid phosphorylation 2 0.285734958 regulation of protein biosynthesis 26 0.240218041 regulation of protein catabolism 1 0.512727273 regulation of protein kinase activity 42 0.261029412 regulation of protein metabolism 31 0.25462963 regulation of protein secretion 3 0.512727273 regulation of protein transport 2 0.373233909 regulation of protein-nucleus import 2 0.373233909 regulation of proteolysis and peptidolysis 1 0.512727273 regulation of proton transport 2 0.171340328 regulation of receptor mediated endocytosis 1 0.444444444 regulation of secretion 8 0.504179466 regulation of signal transduction 74 0.316705687 regulation of sister chromatid cohesion 1 0.489711934 regulation of small GTPase mediated signal transduction 1 0.137472284 regulation of steroid biosynthesis 1 0.091324201 regulation of steroid metabolism 1 0.091324201 regulation of synaptic plasticity 1 0.452054795 regulation of transcription 152 0.238649941 regulation of transcription factor-nucleus import 2 0.373233909 "regulation of transcription\, DNA-dependent " 142 0.236461388 regulation of transferase activity 42 0.261029412 regulation of transforming growth factor beta receptor signaling pathway 1 0.074879227 regulation of translation 21 0.212598425 regulation of translational initiation 3 0.225806452 regulation of transport 9 0.307692308 regulation of tumor necrosis factor-alpha biosynthesis 1 0.113402062 regulation of tyrosine phosphorylation of STAT protein 1 0.287066246 regulation of tyrosine phosphorylation of Stat3 protein 1 0.287066246 regulation of urothelial cell proliferation 1 0.444444444 regulation of vascular endothelial growth factor receptor signaling pathway 1 1.040816327 regulation of vasodilation 4 0.429520344 regulation of viral genome replication 1 0.139393939 regulation of viral life cycle 1 0.139393939 reproduction 68 0.284639336 reproductive physiological process 22 0.395035792 respiratory gaseous exchange 6 0.439620041 respiratory tube development 2 0.289167126 response to DNA damage stimulus 103 0.294294294 response to UV 2 0.29172107 response to abiotic stimulus 154 0.367813967 response to antibiotic 1 0.653658537 response to bacteria 13 0.192 response to biotic stimulus 258 0.331625782 response to carbohydrate stimulus 1 0.123529412 response to chemical substance 68 0.379822897 response to drug 15 0.392226148 response to endogenous stimulus 109 0.275132275 response to ethanol 2 1.290229885 response to external biotic stimulus 115 0.284394251 response to external stimulus 404 0.311273009 response to extracellular stimulus 3 0.13961039 response to heat 2 0.066602882 response to hormone stimulus 5 0.120743034 response to hypoxia 4 0.204289625 response to inorganic substance 5 0.205555556 response to light 14 0.483861531 response to light intensity 1 0.177033493 response to metal ion 5 0.205555556 response to nutrients 3 0.13961039 response to organic substance 9 0.481481481 response to osmotic stress 2 0.622939694 response to oxidative stress 24 0.439560583 response to oxygen radicals 2 0.95226066 response to pH 1 1.669064748 response to pathogen 9 0.192 response to pathogenic bacteria 8 0.191854923 "response to pest\, pathogen or parasite " 112 0.278397843 response to radiation 23 0.310580205 response to reactive oxygen species 2 0.95226066 response to starvation 1 0.569230769 response to sterol depletion 1 0.432098765 response to stimulus 664 0.315367988 response to stress 345 0.294294294 response to superoxide 1 1.300884956 response to temperature 3 0.098814229 response to toxin 10 0.400902771 response to unfolded protein 20 0.209171661 response to virus 3 0.304918033 response to wounding 126 0.292537314 response to xenobiotic stimulus 11 0.326139089 retinal metabolism 1 0.331707317 retinoic acid metabolism 1 0.331707317 retinol metabolism 4 0.428335618 rhodopsin mediated phototransduction 3 0.142433234 rhythmic process 14 0.295981663 ribonucleoside biosynthesis 1 0.081325301 ribonucleoside diphosphate biosynthesis 1 0.236947791 ribonucleoside diphosphate catabolism 1 0.084158416 ribonucleoside diphosphate metabolism 2 0.160553104 ribonucleoside metabolism 6 0.426975123 ribonucleoside monophosphate biosynthesis 11 0.337931034 ribonucleoside monophosphate catabolism 2 0.533266424 ribonucleoside monophosphate metabolism 11 0.337931034 ribonucleoside triphosphate biosynthesis 8 0.505784542 ribonucleoside triphosphate catabolism 2 0.160173338 ribonucleoside triphosphate metabolism 11 0.336283186 ribonucleotide biosynthesis 19 0.395 ribonucleotide catabolism 5 0.204861111 ribonucleotide metabolism 22 0.33710711 ribosome assembly 1 0.085648148 ribosome biogenesis 22 0.304905705 ribosome biogenesis and assembly 23 0.29342723 second-messenger-mediated signaling 73 0.311418685 secondary metabolism 18 0.428246754 secretion 92 0.308008193 secretory pathway 67 0.278317152 segment specification 2 0.830399641 segmentation 4 0.17208762 sensory perception 175 0.313901345 sensory perception of chemical stimulus 9 0.369747899 sensory perception of light 117 0.246537396 sensory perception of mechanical stimulus 53 0.368539326 septin ring assembly 1 0.115485564 septin ring organization 1 0.115485564 serine family amino acid biosynthesis 8 0.263114429 serine family amino acid catabolism 4 0.259567267 serine family amino acid metabolism 13 0.279069767 sex determination 2 0.801254898 sex differentiation 14 0.24764278 sexual reproduction 67 0.276595745 signal complex formation 3 0.856435644 signal peptide processing 2 0.372792602 signal transduction 995 0.309782609 single strand break repair 2 0.364257479 sister chromatid cohesion 2 0.489835887 sister chromatid segregation 20 0.179575015 skeletal development 68 0.356017806 small GTPase mediated signal transduction 22 0.333992808 small molecule transport 2 0.17210221 smooth muscle contraction 3 0.336601307 snRNA transport 1 0.404255319 snRNA-nucleus export 1 0.404255319 snRNP protein-nucleus import 1 0.381188119 sodium ion homeostasis 2 0.230779055 sodium ion transport 54 0.23973293 somatic muscle development 2 0.142540153 sperm motility 1 0.35046729 spermatid development 3 0.246268657 spermatid differentiation 3 0.246268657 spermatogenesis 40 0.272355843 spermidine metabolism 2 0.47731995 spermine metabolism 1 0.417647059 sphingoid biosynthesis 1 0.091324201 sphingoid metabolism 11 0.283333333 sphingolipid biosynthesis 4 0.2645909 sphingolipid catabolism 6 0.299836602 sphingolipid metabolism 22 0.282843137 sphingomyelin metabolism 3 0.305555556 spliceosome assembly 5 0.264631043 stem cell maintenance 1 0.137472284 steroid biosynthesis 23 0.204359673 steroid catabolism 7 0.227074236 steroid metabolism 72 0.216833281 sterol biosynthesis 13 0.188908146 sterol catabolism 4 0.23965319 "sterol depletion response\, sterol regulatory element binding-protein cleavage " 1 0.432098765 sterol metabolism 44 0.216478295 sterol transport 2 0.228255542 stress-activated protein kinase signaling pathway 20 0.348288924 striated muscle contraction 29 0.189873418 succinyl-CoA metabolism 1 0.248175182 sugar utilization 1 0.554323725 sulfate transport 2 1.364402452 sulfur amino acid biosynthesis 7 0.264094955 sulfur amino acid metabolism 14 0.368289417 sulfur amino acid transport 2 0.196527151 sulfur compound biosynthesis 13 0.3514377 sulfur metabolism 22 0.335217058 superoxide metabolism 7 0.210416667 superoxide release 1 0.211981567 "symbiosis\, mutualism through parasitism " 14 0.271943961 symbiotic interaction between host and other organism 14 0.271943961 synapse organization and biogenesis 4 0.335946969 synaptic transmission 115 0.369158879 synaptic vesicle endocytosis 1 0.468 synaptic vesicle exocytosis 1 0.43697479 synaptic vesicle transport 3 0.43697479 synaptogenesis 4 0.335946969 tRNA 3'-processing 1 1.054054054 tRNA aminoacylation 24 0.35123882 tRNA aminoacylation for protein translation 24 0.35123882 tRNA metabolism 43 0.350364964 tRNA modification 27 0.350364964 tRNA processing 21 0.290322581 tRNA transcription 2 1.632834829 taxis 22 0.341165815 terpene biosynthesis 1 0.188908146 terpene metabolism 2 0.260307732 terpenoid biosynthesis 1 0.188908146 terpenoid metabolism 2 0.260307732 tetracycline transport 4 0.678208556 tetraterpenoid biosynthesis 1 0.188908146 tetraterpenoid metabolism 1 0.188908146 thermoregulation 1 0.569230769 thiamin transport 1 0.364754098 thymic T cell selection 1 0.36682243 thyroid hormone metabolism 1 0.104575163 toxin metabolism 1 1.977272727 transcription 478 0.276708685 transcription factor-nucleus import 2 0.373233909 transcription from RNA polymerase I promoter 1 0.125319693 transcription from RNA polymerase II promoter 126 0.238649941 transcription from RNA polymerase III promoter 3 0.451162791 transcription initiation 25 0.341463415 transcription termination 2 0.63167784 transcription-coupled nucleotide-excision repair 1 0.119565217 "transcription\, DNA-dependent " 170 0.260156373 transforming growth factor beta receptor signaling pathway 12 0.259336843 transition metal ion homeostasis 14 0.313931951 transition metal ion transport 14 0.212234433 translation 65 0.273049645 translational elongation 14 0.225128774 translational initiation 9 0.225806452 translational termination 4 0.199054023 transmembrane receptor protein serine/threonine kinase signaling pathway 20 0.259336843 transmembrane receptor protein tyrosine kinase activation (dimerization) 1 0.709580838 transmembrane receptor protein tyrosine kinase signaling pathway 44 0.36882938 transmembrane receptor protein tyrosine phosphatase signaling pathway 9 0.252900232 transmission of nerve impulse 118 0.369453389 transport 1058 0.295798742 traversing start control point of mitotic cell cycle 2 0.424388209 trehalose metabolism 1 0.19112628 triacylglycerol biosynthesis 1 1.243055556 triacylglycerol catabolism 1 1.243055556 triacylglycerol metabolism 7 0.371727749 tricarboxylic acid cycle 14 0.144544582 tricarboxylic acid cycle intermediate metabolism 9 0.14861461 tricarboxylic acid transport 1 0.105839416 tryptophan catabolism 2 0.664761198 tryptophan metabolism 2 0.664761198 tube development 3 0.31884058 tubulin folding 3 0.224358974 tumor necrosis factor-alpha biosynthesis 1 0.113402062 two-component signal transduction system (phosphorelay) 8 0.246252205 tyrosine catabolism 4 0.163107606 tyrosine metabolism 4 0.163107606 tyrosine phosphorylation of STAT protein 1 0.287066246 ubiquinone biosynthesis 3 0.544444444 ubiquinone metabolism 3 0.544444444 ubiquitin cycle 256 0.265734589 unfolded protein response 2 1.530969191 urea cycle 2 0.183580374 urea cycle intermediate metabolism 5 0.159468439 urea transport 1 0.953488372 ureteric bud development 1 0.807407407 urogenital system development 2 0.524074074 uronic acid metabolism 1 0.382978723 uroporphyrinogen III biosynthesis 1 0.248175182 uroporphyrinogen III metabolism 1 0.248175182 urothelial cell proliferation 1 0.444444444 vacuolar acidification 1 0.077419355 vacuolar protein catabolism 1 0.577586207 vacuolar transport 3 0.598746082 vacuole organization and biogenesis 2 0.65416346 valine metabolism 3 0.160883281 vascular endothelial growth factor receptor signaling pathway 1 1.040816327 vasculature development 25 0.327272727 vasculogenesis 4 0.474620036 vasoconstriction 1 0.612244898 vasodilation 4 0.429520344 ventral midline development 1 0.38547486 vesicle docking 1 0.143459916 vesicle targeting 3 0.408805031 vesicle-mediated transport 186 0.27249191 viral entry into host cell 7 0.371794872 viral genome replication 6 0.266332219 viral infectious cycle 11 0.259493671 viral transmission 2 0.566591579 virion attachment 2 0.566591579 virion transport 2 0.566591579 virus-host interaction 3 0.371794872 visual perception 117 0.246537396 vitamin A metabolism 9 0.179487179 vitamin B6 biosynthesis 1 0.375 vitamin B6 metabolism 1 0.375 vitamin biosynthesis 2 0.330038976 vitamin metabolism 21 0.370558376 vitamin transport 9 0.28125 water homeostasis 3 0.481481481 water transport 3 0.764397906 water-soluble vitamin biosynthesis 2 0.330038976 water-soluble vitamin metabolism 9 0.375 wound healing 51 0.307692308 xenobiotic metabolism 11 0.326139089 zinc ion homeostasis 1 0.130699088